Late Recurrence of Lupus Nephritis in a Renal Transplant Recipient: Response to Mycophenolate Mofetil
作者:
Tejinder Ahuja,
Judy Boughton,
Vasanta Weiss,
Amir Memon,
August Remmers,
Srinivasan Rajaraman,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 2001)
卷期:
Volume 322,
issue 3
页码: 166-169
ISSN:0002-9629
年代: 2001
出版商: OVID
关键词: Renal allograft;Mycophenolate mofetil;Lupus nephritis
数据来源: OVID
摘要:
Clinically significant recurrence of lupus nephritis in the renal allograft is low, with an incidence of 1 to 3%, and usually occurs within the first 6 years after transplantation. We report an unusual case of a patient with end-stage renal disease caused by lupus nephritis who received a kidney transplant from a living relative; 13 years later, the patient had a severe recurrence of diffuse proliferative lupus nephritis. The patient relapsed after receiving intravenous cyclophosphamide therapy and had a partial response to oral mycophenolate mofetil. In this report we review the risk factors for the recurrence of the systemic lupus erythematosus in the kidney graft and the anti-lupus activity of mycophenolate mofetil.
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