Disseminated strongyloidiasis in AIDSuncommon but important
作者:
Mark Gompels,
Jeannie Todd,
Barry Peters,
Janice Main,
Anthony Pinching,
期刊:
AIDS
(OVID Available online 1991)
卷期:
Volume 5,
issue 3
页码: 329-332
ISSN:0269-9370
年代: 1991
出版商: OVID
关键词: AIDS;Strongyloides;hyperinfection;thiabendazole
数据来源: OVID
摘要:
DisseminatedStrongyloides stercoralisinfection is a rare and severe but treatable complication of AIDS. We present a case where this infection was successfully treated and review the available literature. Cases may present many years after they have left an area endemic forStrongyloidesinfection, emphasizing the need for a full travel history. Symptoms are typically gastrointestinal and pulmonary, with infiltrates often seen on chest radiography. Diagnosis requires stool examination and biopsy of affected sites. Treatment with repeated courses of thiabendazole (25 mg/kg twice daily for 5 days) was successful in our case, but maintenance regimens have not yet been defined. The relative rarity of this complication of AIDS suggests that, where both infections are present, disseminated strongyloidiasis only arises either when HIV-induced immunodeficiency is profound or, possibly, when it is accompanied by impaired granulopoiesis.
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