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Inactivation of pentagastrin by the liver

 

作者: J. H. Wyllie,   B. H. Stagg,   J. M. Temperley,  

 

期刊: British Journal of Surgery  (WILEY Available online 1974)
卷期: Volume 61, issue 1  

页码: 22-26

 

ISSN:0007-1323

 

年代: 1974

 

DOI:10.1002/bjs.1800610107

 

出版商: John Wiley&Sons, Ltd.

 

数据来源: WILEY

 

摘要:

AbstractPentagastrin is deamidated to pentagastrin acid by high‐speed supernatant preparations obtained from rat, dog and human liver. The product, which contains all the amino acids in the parent substance, is biologically inactive. Experiments with pentagastrin labelled with carbon 14 indicate that this reaction also occurs in intact dog

 

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