The Pathogenesis of Gallstones
作者:
SmithBernard F.,
LaMontJ. Thomas,
期刊:
Hospital Practice
(Taylor Available online 1984)
卷期:
Volume 19,
issue 12
页码: 93-104
ISSN:2154-8331
年代: 1984
DOI:10.1080/21548331.1984.11702958
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Intensive investigations into the mechanism of gallstone formation have revealed that cholesterol supersaturation of the bile is a necessary but insufficient condition for cholelithiasis. A defect in the regulation of monohydrate crystal nucleation appears to be the most critical factor. The possible influences of serum apoproteins, of gallbladder mucin, and of biliary sludge are discussed.
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