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Detection of Gene Rearrangements in Reactive Lymphoid Processes

 

作者: OrphanosV.,   AnagnostouD.,   PapadakiTh.,   ManiatisG. M.,   AthanassiadouA.,  

 

期刊: Leukemia&Lymphoma  （Taylor Available online 1993）
卷期: Volume 9, issue 1-2  

页码: 103-106

 

ISSN:1042-8194

 

年代: 1993

 

DOI:10.3109/10428199309148511

 

出版商: Taylor&Francis

 

关键词: Gene rearrangements;reactive;lymphoproliferations

 

数据来源: Taylor

 

摘要:

We report the immunohistologic and the genotypic analysis of lymph node biopsies from 23 cases of reactive processes, and two cases of atypical lymphoproliferations (AL). Clonal gene rearrangements were detected in 5 cases of proven reactive processes as well as in both AL, in which no signs of malignancy were detected during the phenotypic analysis. No patient, apart from the two AL cases, showed any progression to malignancy during a follow-up period of 28–43 months after the initial biopsy.

 

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