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Viral hepatitis in the United States, 1970–1973an analysis of morbidity trends and the impact of HBSAg testing on surveillance and epidemiology

 

作者: JOHN,   BRYAN MICHAEL,  

 

期刊: The American Journal of the Medical Sciences  (OVID Available online 1975)
卷期: Volume 270, issue 2  

页码: 271-282

 

ISSN:0002-9629

 

年代: 1975

 

出版商: OVID

 

关键词: Viral hepatitis;Morbidity trends;Surveillance;Epidemiology;HBsAg testing

 

数据来源: OVID

 

摘要:

Morbidity and surveillance data on viral hepatitis cases in the United States since 1970 has revealed plateauing of case rate, continued failure to observe seasonal variation, more general geographic distribution of cases, and persistence, although at progressively lower levels, of highest rates in males 15–29 years of age. Based on results of HBSAg testing, as much as 24 per cent of hepatitis B may be misdiagnosed by physicians and from 18 to 46 per cent of reported cases can be classified hepatitis B, thus suggesting that hepatitis B may account for up to one-half the recognized viral hepatitis in this country. HBSAg-negative hepatitis still seems commonly acquired through close personal contact; hepatitis B patients 15–29 years of age also commonly have personal contact association. Parenteral drug abuse and transfusion of blood and blood products continue to play a role in dissemination of hepatitis B, but hepatitis B seems to account for only about one half of all reported transfusion-associated hepatitis. Case fatality rates for reported cases appear to increase with age but are not higher for HBSAg positive patients than for negative patients.

 

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