Serotoninergic neurites in senile plaques in cingulate cortex of aged nonhuman primate
作者:
Cheryl A. Kitt,
Lary C. Walker,
Mark E. Molliver,
Donald L. Price,
期刊:
Synapse
(WILEY Available online 1989)
卷期:
Volume 3,
issue 1
页码: 12-18
ISSN:0887-4476
年代: 1989
DOI:10.1002/syn.890030103
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Aging;Amyloid;Old monkeys
数据来源: WILEY
摘要:
AbstractIn immunocytochemical studies, a polyclonal antiserotonin antibody was used to visualize fibers within the cingulate cortex of young and aged rhesus monkeys. Intricate and distinct patterns of serotoninergic processes were seen in anterior and posterior segments of cingulate cortex (Brodmann areas 24 and 23). In these regions of cortex, many multivaricose serotonin‐immunoreactive axonal swellings were identified, and some of these immunostained neurites were associated with deposits of amyloid. These observations suggest that serotoninergic processes are involved in the formation of senile plaques in neocortex of aged macaque
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