NewBooks from theRoyal Society ofChemistry Molecular Biology and Biotechnology Molecular Biology and Biotechnology Edited by J.M. Walker and E.B. Gingold I ' Special Publicution No.54(1986) Softcover 348pp ISBN 0 85186 985 8 Price €25.00 ($45.00) I Edited by J MWalker and E B Gingold I This book covers the recent advances made in the field of biotechnology and is aimed not at expert biotechnologists but at scientific workers with little or no previous experience in this field. The contributions in this book should thus be seen as primarily having a teaching function. The book should prove of interest both to undergraduates studying for biological or chemical qualifications and to scientific workers from other fields who need a basic introduction to this rapidly expanding area.Contents Products from Micro-organisms; An introduction to Genetic Engineering; The Expression of Foreign DNA in bcherichia coli; Cloning in Brewer's Yeast Succharomyces cerevisiae; Cloning in Mammalian Cells; The Genetic Manipulation of Crop Plants; The Application of Genetic Engineering to the Production of Pharmaceutical Compounds; Clinical Applications of Molecular Biology; Generation and Use of cDNA Clones for Studying Gene Expression; Enzyme Technology Towards Usable Catalysts; Applications or Biotechnology to Chemical Production; Enzyme Recovery and Purification Downstream Processing; Biosensors; Enzyme Engineering. ~-Ordering Orders should be sent to The Royal Society of Chemistry Distribution Centre Blackhorse Road Letchworth Herts SG6 1 HN U.K.Non-RSC Members and US$ pricesquoted.RSC Members are entitled to a discount on most RSC books and journals details available horn:Assistant Membership Officer The Royal Society of Chemistry 30 Russell Square London WC 1B 5DT. Pharmacokinetics of Cardiovascular Central Nervous System and Antimicrobial Drugs by P.G. Welling and F. L. S. Tse Hardcover 468pp JSBN 0 851 86 937 8 Price €39.00 ($7 1.OO) During the last 20 years the drug industry and the practice of medicine have expanded at an incredible rate. This has been due to the combined influences of a number of factors including rapid advances in pharmacology and pathology and accompanying advances in such diverse areas as pharmacodynamics pharmacokinetics and the developmentof sophisticated drug delivery systems.The last of these has been the focus of frenzied activity during the last ten years and is likely to continue for some time. More recent advances in immunopharmacology and the use of monoclonal antibodies have provided further impetus to the quest for new drugs in many therapeutic areas. Three major areas of drug research and development which have undergone considerable changes in recent years include cardiovascular agents drugs acting on the central nervous system (CNS) and antimicrobial agents. This book reviews developments which have taken place in these subjects from 1970 to the early 1980's. Contents Cardiovascular Drugs Cardiac Glycosides and Other Cardiotonic Agents; Antiarrhythmic and Antianginal Agents; Beta-Adrenergic Receptor Antagonists; Diuretics; Other Antihypertensive Agents; Anticoagulants.Drugs Acting on the Central Nervous System; Antidepressants; Antipsychotic Agents; Sedatives Hypnotics and Tranquilizers; Anticonvulsants. Antimicrobial Agents Penicillins; Cephalosporins and Cephamycins; Tetrecyclines; Aminoglycosides; Sulfonamides; Erythromycin Its Salts and Esters; Other Antimicrobial Agents. CompoundIndex ROYAL SOCIETYOF CHEMISTRY Information Services SPECIALIST PERIODICALREPORTS Copies of back issues of the Specialist Periodical Reports from which Natural Product Reports is derived are still available as follows Aliphatic and Related BiosynthesisVOID7 Natural Product Senior Reporters R.B.Herbert and T.J. Simpson A review of the literature published during 1979,1980 and 1981. Chemistry VOID3 Brief Contents The Biosynthesis of Polyketides; Phenolic Compounds Senior Reporter F.D. Gunstone Derived from Shikimate; The Biosynthesis of C5-C20 Terpeniod This third volume in theseries reviews the literature published Compounds; The Biosynthesis of Alkaloids. during 1980 and 1981. Hardcover232pp 0 851 86 553 4 Brief Contents Price €33.00 ($59.00) Natural Aceiylenic and Olefinic Compounds; Acyclic Still available Terpenoids; Insect Pheromones and Related Natural Vol.1 (1971) 0 851 86 503 8 €20.00 ($36.00) Products; Prostaglandins and Leukotrienes; Fatty Acids and V01.2(1972)0851865135 €21.00($38.00) Glycerides; Lipids; Olefinic Microbial Metabolites including Vo1.3 (1 973) 0 851 86 523 2 €21 .OO ($38.00) Macrocyclic Compounds.Vo1.4 (1 974) 0 851 86 533 X €24.00 ($43.00) Vo1.5 (1 975) 0 851 86 543 7 €32.00 ($57.00) Hardcover374pp 0 851 86 662 X Price €42.00 ($75.00) Vo1.6 (1 977-78) 0 851 86 990 4 €48.00 ($86.00) Stillavailable Special Package Price (Vols.1-7)S108.00 ($1 93.00) VOI 1 (1 976-77) 0 851 86 642 5 €35.00 ($63.00) VOI 2 (1 978-79) 0 851 86 652 5 €49.00 ($88.00) Special Package Price (Vols. 1-3)€79.00 ($1 41.OO) Terpenoids and The Alkaloids VOI. 13 Senior Reporter J.R. Hanson Senior Reporter M.F. Grundon This twelfth volume in the series covers the literature A review of the literature published between July 198 1 and published between September 1980 and August 1981.June 1982. Brief Contents Brief Contents Part I:Terpenoids Monoterpenoids; Sesquiterpenoids; Biosynthesis; Pyrrolidine Piperidine and Pyridine Alkaloids; Diterpenoids; Triterpenoids; Carotenoids Tropane Alkaloids; Pyrrolizidine Alkaloids; lndolizidine and Polyterpenoids. Alkaloids; Quinolizidine Alkaloids; Quinoline and Acridone Part II:Steroids Physical Methods Steroid Reactions and Alkaloids; O-Phenylethylamines and the lsoquinoline Pa rtia ISyntheses. Alkaloids; Aporphinoid Alkaloids; Amarylidaceae Alkaloids; Hardcover366pp 0 851 86 356 6 Erythrina and Related Alkaloids; lndole Alkaloids; Price€62.00 ($1 11.OO) fycopodiumAlkaloids; Diterpeniod Alkaloids; Steroidal Still available Alkaloids; Miscellaneous Alkaloids.Vol. 1 (1 969-70)0 851 86 256 X €26.00 ($47.00) Hardcover343p 0 85186 367 1 Vol. 2 (1 970-71) 0 85186 266 7 €23.00 ($41 .OO) Price €33.00 ($59.00) Vol. 3 (1 971 -72) 0 851 86 276 4 €26.00 ($47.00) still available VOI. 4 (1 972-73) 0 851 86 286 1 €30.00 ($54.00) VOI. 1 (1969-70) 0 851 86 257 8 €24.00 ($43.00) Vol. 5 (1 973-74)0 851 86 296 9 €31 .OO ($56.00) Vol. 2 (1970-71) 0 85186 267 5 €20.00 ($36.00) Vol. 6 (1 974-75) 0 851 86 306 X €31.OO ($56.00) Vol. 3(1971-72)085186277 2E21.00 ($38.00) Vol. 7 (1 975-76) 0 851 86 31 6 7 €36.00 ($65.00) VOI. 4 (1 972-73) 0 851 86 287 X €24.00 ($43.00) Vol. 8 (1 976-77) 0 851 86 326 4 €33.00 ($59.00) Vol. 5 (1 973-74) 0 851 86 297 7 €26.00 ($47.00) Vol.9 (1 977-78) 0 851 86 650 6 €40.00 ($72.00) Vol. 6 (1974-75) 0 851 86 307 8 €28.00 ($50.00) VOl.10 (1 978-79) 0 851 86 336 1 €54.00 ($97.00) Vol. 7 (1975-76) 0 851 86 31 7 5 €35.00 ($65.00) Vol. 1 1 (1 979-80)0 851 86 346 9 €54.00 ($97.00) Vol. 8 (1 976-77) 0 851 86 327 8 €34.00 ($61.OO) Special package price (Vols 1 -1 2) C254.00 ($453.00) Vol. 9 (1 977-78) 0 851 86 660 2 €38.00 ($68.00) VOl.10 (1 978-79) 0 851 86 337 X €61.OO ($1 09.00) Non-RSC Members and US$ prices quoted. RSC Members are VOl.11 (1979-80) 085186347 7 €61.00 ($109.00) entitled to a discount on most RSC books and journals. Details VOl.12 (1 980-81) 0 851 86 357 4 €67.00 ($1 20.00) available fr0m:TheAssistant Membership Officer The Royal Society Special package price (Vols 1-1 3) €229.00 ($409.00) of Chemistry,30 Russell Square London WC1 B 5DT. Ordering ROYAL SOCIETYOF Orders should be sent to CHEMISTRY The Royal Society of Chemistry Distribution Centre Information Blackhorse Road Letchworth Herts SG6 1HN U.K. Services