Exfoliation syndrome

 

作者: Robert Ritch,  

 

期刊: Current Opinion in Ophthalmology  (OVID Available online 2001)
卷期: Volume 12, issue 2  

页码: 124-130

 

ISSN:1040-8738

 

年代: 2001

 

出版商: OVID

 

数据来源: OVID

 

摘要:

Exfoliation syndrome (XFS) is an age-related disorder of the extracellular matrix characterized by production and progressive accumulation of small, white deposits of a fibrillar extracellular material in many ocular tissues, most commonly seen on the pupillary border and anterior lens capsule. Characteristic signs of pigment liberation and deposition throughout the anterior segment aid in the diagnosis. Exfoliation syndrome predisposes to both open-angle and angle-closure glaucoma, and to capsular rupture, zonular dehiscence, and vitreous loss during cataract extraction. Exfoliation syndrome is associated with ocular and perhaps systemic ischemia. The exact chemical composition of exfoliation material remains unknown. Medical, laser, and surgical therapy are similar to treatment of primary open-angle glaucoma.

 

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