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Analysis of Nitrofurantoin in Human Plasma by High Pressure Liquid Chromatography

 

作者: WilliamD. Mason,   JohnD. Conklin,  

 

期刊: Analytical Letters  （Taylor Available online 1987）
卷期: Volume 20, issue 4  

页码: 617-626

 

ISSN:0003-2719

 

年代: 1987

 

DOI:10.1080/00032718708067993

 

出版商: Taylor & Francis Group

 

关键词: Nitrofurantoin;HPLC

 

数据来源: Taylor

 

摘要:

An HPLC method for the analysis of nitrofurantoin (NTR) in human plasma has been developed and evaluated. This method is based on a selective extraction and reverse-phase chromatography which results in chromatograms with 2400 to 2500 theoretical plates for NTR and the internal standard (furazolidone). The method is highly reproducible and has been validated over the range of 5 to 4000 ng/ml.

 

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