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Pedigree Study of Familial Alzheimer Disease

 

作者: PowellDiane,   FolsteinMarshal F.,  

 

期刊: Journal of Neurogenetics  （Taylor Available online 1984）
卷期: Volume 1, issue 2  

页码: 189-197

 

ISSN:0167-7063

 

年代: 1984

 

DOI:10.3109/01677068409107085

 

出版商: Taylor&Francis

 

关键词: Alzheimer disease;pedigree study

 

数据来源: Taylor

 

摘要:

Twenty-one families with familial Alzheimer disease were ascertained in a dementia clinic and assessed by multiple family interviews. Eight autopsies were reviewed. The age of onset varied from 25 to 85. Seven pedigrees showed evidence of 3 generation transmission. Paternal age of the founders of 4 lines which could be assessed was higher than controls.

 

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