Effect of Model Traumatic Injury on Hepatic Drug-metabolizing Enzymes
作者:
ELMER RAUCKMAN,
GERALD ROSEN,
STEPHEN POST,
SCOTT GILLOGLY,
期刊:
The Journal of Trauma: Injury, Infection, and Critical Care
(OVID Available online 1980)
卷期:
Volume 20,
issue 10
页码: 884-886
ISSN:0022-5282
年代: 1980
出版商: OVID
数据来源: OVID
摘要:
Abdominal aorta ligation in rats was found to be a suitable model traumatic injury for the study of the effect of trauma on drug-metabolizing enzymes. This procedure was found to result in a rapid decrease in both cytochrome P-450 and mixed function amine oxidase activities. Recovery of mixed function amine oxidase activity was slower than recovery of cytochrome P-450 activity.
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