Ventricular Pressure‐Volume Relationships and Oxygen Consumption in Fibrillation and Arrest
作者:
R. Monroe,
Gordon French,
期刊:
Circulation Research
(OVID Available online 1960)
卷期:
Volume 8,
issue 1
页码: 260-266
ISSN:0009-7330
年代: 1960
出版商: OVID
数据来源: OVID
摘要:
Pressure-volume relationships and myocardial oxygen consumption (V˙O2) were obtnined in an isolated heart during ventricular fibrillation, potassium-induced arrest, and isovolumetric contractions. The heart was found to be less distensible in fibrillation than in diastole or arrest. The V˙O2increased from 4.6 to 14.6 cc./100 Gm. LV/min. as the fibrillating ventricle was distended. During arrest the V˙O2remained constant despite ventricular distention. When the fibrillating ventricle was distended beyond a critical point coronary flow was compromised and the V˙O2decreased. Beyond and only beyond this point could the V˙O2be increased by the greater coronary flow induced by a higher perfusion pressure.
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