Effect of low-dose glucocorticoid treatment on dentin formation and dentinal caries in rats
作者:
HuumonenSisko,
PajariUlla,
BäckmanTuula,
TjäderhaneLeo,
LarmasMarkku,
期刊:
Acta Odontologica Scandinavica
(Taylor Available online 1996)
卷期:
Volume 54,
issue 5
页码: 282-286
ISSN:0001-6357
年代: 1996
DOI:10.3109/00016359609003539
出版商: Taylor&Francis
关键词: Caries;dentinogenesis;glucocorticoids;rats
数据来源: Taylor
摘要:
The effect of a low dose of glucocorticoids on dentin formation and progression of dental caries was studied in young rats. The animals were inoculated in the mouth withStreptococcus sobrinusand fed ad libitum a high-sucrose, a high-starch, or a reference diet. The cortisone or placebo pellet was implanted subcutaneously in the back of the necks of the animals. After a 6-week experimental period the areas of dentin formation and dentinal caries were quantified planimetrically. Schiff s staining was used to classify caries. Cortisone reduced the dentin formation both in high-starch and reference diets, but it did not further affect the reducing effect of the high-sucrose diet on dentin formation. Cortisone did not affect the number or severity of dentinal carious lesions.
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