Pilot Study to Determine the Interaction of Oxiracetam with Antiepileptic Drugs
作者:
Anthonie van Wieringen,
Jaap W.A. Meijer,
Walter van Emde Boas,
Theodorus A.C. Vermeij,
期刊:
Clinical Pharmacokinetics
(ADIS Available online 1990)
卷期:
Volume 18,
issue 4
页码: 332-338
ISSN:0312-5963
年代: 1990
出版商: ADIS
数据来源: ADIS
摘要:
Oxiracetam, a nootropic drug, could be of potential use in the treatment of memory disturbances in patients with epilepsy who are using antiepileptic drugs. The half-life of oxiracetam appears to be influenced by the concomitant use of carbamazepine or valproic acid, necessitating more frequent administration of oxiracetam than is recommended for other conditions. No effect was observed on the serum concentrations of these antiepileptic drugs by oxiracetam. Long term concurrent use of oxiracetam and antiepileptic agents does not appear to be contraindicated.
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