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Transient coagulation abnormalities after incompatible blood transfusion

 

作者: PATRICK McKENNA,   HAROLD SCHEINMAN,  

 

期刊: Critical Care Medicine  (OVID Available online 1975)
卷期: Volume 3, issue 1  

页码: 8-12

 

ISSN:0090-3493

 

年代: 1975

 

出版商: OVID

 

数据来源: OVID

 

摘要:

This report describes an unusual hemolytic transfusion reaction. A group O donor was inadvertently transfused with 100 ml of group A red cells during the course of plasmapheresis. Granulocytopenia, thrombocytopenia, hypofibrinogenemia and low levels of factors V, VIII, and IX developed immediately after the infusion. The levels of the cellular elements and coagulation proteins returned to normal in less than an hour; too rapid for ade novosynthesis after consumption of coagulation proteins. We postulate that activation of the kinin system was responsible for the phenomena rather than intravascular coagulation with secondary fibrinolysis.

 

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