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Recognition of Sialic Acid Using Molecularly Imprinted Polymer

 

作者: A. Kugimiya,   J. Matsui,   T. Takeuchi,   K. Yano,   H. Muguruma,   A.V. Elgersma,   I. Karube,  

 

期刊: Analytical Letters  （Taylor Available online 1995）
卷期: Volume 28, issue 13  

页码: 2317-2323

 

ISSN:0003-2719

 

年代: 1995

 

DOI:10.1080/00032719508000375

 

出版商: Taylor & Francis Group

 

关键词: molecular imprinting;sialic acid;sugar;liquid chromatography

 

数据来源: Taylor

 

摘要:

The molecular imprinting technique was applied for the preparation of a polymer selective for sialic acid. To evaluate its binding ability the molecularly imprinted polymer obtained was used as a stationary phase in liquid chromatography. The polymer showed pH-dependent characteristics for binding: an optimum specificity to sialic acid at pH 8.1 and a higher affinity with group selectivity forcis-diol containing sugars at higher pH.

 

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