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The Use of Capacity Factors with Micro-HPLC as a Descriptors in Quantitative-Structure-Activity Relationships

 

作者: Kiyokatsu Jinno,  

 

期刊: Analytical Letters  （Taylor Available online 1984）
卷期: Volume 17, issue 3  

页码: 183-190

 

ISSN:0003-2719

 

年代: 1984

 

DOI:10.1080/00032718408065277

 

出版商: Taylor & Francis Group

 

关键词: micro-HPLC;capacity factors as a descriptor;QSAR work

 

数据来源: Taylor

 

摘要:

The capcity factors determined by reversed-phase micro high performance liquid chromatography (micro-HPLC) can be used as one of the descriptors in Quantitative-Structure-Activity-Relationships (QSAR) studies. The present method gives a more simple and convenient way to study relationships between physicochemical properties and biological activities of some drugs.

 

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