Long-Term Effects of Alloxan Induced Diabetes on the Nucleus ventralis posterolateralis in the Thalamus of the Rat
作者:
S.S.W. Tay,
W.C. Wong,
期刊:
Cells Tissues Organs
(Karger Available online 1992)
卷期:
Volume 144,
issue 1
页码: 51-58
ISSN:1422-6405
年代: 1992
DOI:10.1159/000147285
出版商: S. Karger AG
关键词: Nucleus ventralis posterolateralis;Thalamus;Rat;Alloxan;Diabetes mellitus
数据来源: Karger
摘要:
The present paper describes the long-term ultrastructural changes in the nucleus ventralis posterolateralis of the thalamus of male Wistar rats after alloxan-induced diabetes. Degenerating dendrites were characterized by an electron-dense cytoplasm with scattered endoplasmic reticulum and ribosomes. Degenerating axon terminals were characterized by an electron-dense cytoplasm and clustering of small spherical agranular vesicles. Degenerating axon terminals formed axosomatic synapses with seemingly normal cell bodies and axodendritic synapses with normal as well as degenerating dendrites. Degenerating axons (both myelinated and unmyelinated) were readily encountered in the neuropil. Activated microglial and astrocytic cells in the neuropil were in the process of phagocytosis or had residua in their cytoplasm.
点击下载:
PDF
(1447KB)
返 回