Effect of Potassium Removal during Hemodialysis on the Plasma Potassium Concentration
作者:
Peter U. Feig,
Alan Shook,
Richard H. Sterns,
期刊:
Nephron
(Karger Available online 1981)
卷期:
Volume 27,
issue 1
页码: 25-30
ISSN:1660-8151
年代: 1981
DOI:10.1159/000182015
出版商: S. Karger AG
关键词: Potassium;Hemodialysis;Hyperkalemia;Chronic renal failure;Urea
数据来源: Karger
摘要:
The effect of potassium removal by hemodialysis on the plasma potassium concentration (PK) was observed during 20 studies on 7 anuric patients. The following was observed: (1) The pattern of change in PK is consistent with at least a two-compartment distribution; hence, in contrast to urea, PK shows a marked postdialytic rebound and the simple equation for solute removal from a single pool cannot predict postdialysis PK. (2) The magnitude of the fall in PK correlated with the predialysis PK; this was not only due to increased potassium removal, but also due to a dependence of the apparent volume of distribution of potassium on the state of potassium balance. The fractional decrement in plasma potassium concentration, contrary to that of urea, is a function of predialysis concentration, and prediction of the effect of dialysis on plasma potassium concentration can assume neither a single pool nor a constant distribution volume for this ion.
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