Superior Epithelial Arcuate Lesions with Soft Contact Lens Wear
作者:
Brien Holden,
Andrew Stephenson,
Serina Stretton,
Padmaja Sankaridurg,
Nicole O’Hare,
Isabelle Jalbert,
Deborah Sweeney,
期刊:
Optometry and Vision Science
(OVID Available online 2001)
卷期:
Volume 78,
issue 1
页码: 9-12
ISSN:1040-5488
年代: 2001
出版商: OVID
关键词: superior epithelial arcuate lesions,;SEALs,;epithelial staining,;soft contact lens,;high Dk
数据来源: OVID
摘要:
BackgroundSuperior epithelial arcuate lesions (SEALs) are an infrequent and often asymptomatic complication of conventional soft contact lens wear. The characteristic arcuate pattern of the full-thickness corneal epithelial lesion usually occurs in the area covered by the upper eyelid, within 2 to 3 mm of the superior limbus in the 10- and 2-o’clock region.MethodsLiterature on SEALs and recent clinical records from clinical trials using two types of prototype high Dk soft contact lenses were reviewed to gain greater insights into the etiology of SEALs.Results and ConclusionsThe reported low incidence of SEALs is partly because SEALs are not usually symptomatic. The etiology of SEALs is multifactorial. Our current hypothesis is that SEALs are produced by mechanical chaffing at the peripheral cornea. This chaffing occurs as a result of inward pressure of the upper lid, in an area where the peripheral corneal topography and lens design, rigidity, and surface characteristics combine to create excessive “frictional” pressure and abrasive shear force on the epithelial surface. Patient characteristics such as gender, age, and specific corneal and lid topographies also appear to influence the occurrence of SEALs. Prototype silicone hydrogel lenses are made from higher modulus materials with surfaces that seem to differ subtly in wettability in some patients. The prevalence of SEALs may well increase with the first generations of these lenses.
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