Controlled trials of Antabuse in alcoholism: the importance of supervision and adequate dosage
作者:
C. Brewer,
期刊:
Acta Psychiatrica Scandinavica
(WILEY Available online 1992)
卷期:
Volume 86,
issue S369
页码: 51-58
ISSN:0001-690X
年代: 1992
DOI:10.1111/j.1600-0447.1992.tb03316.x
出版商: Blackwell Publishing Ltd
关键词: Antabuse;disulfiram;effectiveness;supervision;compliance
数据来源: WILEY
摘要:
AbstractMethods of using Antabuse have changed since its introduction over 40 years ago. Several randomised controlled trials have shown that Antabuse can make a statistically and clinically significant contribution to treatment outcome in alcoholism but only if its administration is carefully supervised. The recent literature is reviewed. Adequate dosage is important and the recommended maximum in some countries is often insufficient. Both prescribes and supervisors of Antabuse need to be aware of the ways in which some patients try to evade medication.
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