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Is Etretinate Dangerous in Papillon-Lefèvre Syndrome?

 

作者: Antonella Tosti,   Patrizia Manuzzi,   Federico Bardazzi,   Angela Costa,  

 

期刊: Dermatology  （Karger Available online 1988）
卷期: Volume 176, issue 3  

页码: 148-150

 

ISSN:1018-8665

 

年代: 1988

 

DOI:10.1159/000248692

 

出版商: S. Karger AG

 

关键词: Papillon-Lefèvre syndrome;Etretinate;Severe infections;Liver abscesses

 

数据来源: Karger

 

摘要:

A 23-year-old girl affected by Papillon-Lefèvre syndrome developed, during Etretinate therapy (1 mg/kg/day), two liver abscesses caused by pyogenic bacteria and a subphrenic abscess. The immunological effects of retinoids may precipitate severe infections in patients with Papillon-Lefèvre syndrome, who probably have a basic, even though not always evident, defect of PMN chemotaxi

 

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