Efficacy and Tolerance of a Miconazole-Benzoyl Peroxide Cream Combination versus a Benzoyl Peroxide Gel in the Topical Treatment of Acne vulgaris
作者:
R. Flückiger,
H.-J. Furrer,
T. Rufli,
期刊:
Dermatology
(Karger Available online 1988)
卷期:
Volume 177,
issue 2
页码: 109-114
ISSN:1018-8665
年代: 1988
DOI:10.1159/000248525
出版商: S. Karger AG
关键词: Acne vulgaris;Benzoyl peroxide;Miconazole
数据来源: Karger
摘要:
62–65% reduction in the number of lesions was obtained in the treatment of 52 patients with acne vulgaris in this randomized single-blind study comparing a 5% benzoyl peroxide/2% miconazole cream (BPO-MCZ) with a 5% benzoyl peroxide gel (BPO). While BPO gel was equally effective in male and female patients (66 and 73% reduction of lesions), the BPO-MCZ cream was significantly more effective in the latter (50 vs. 74% mean reduction of lesions). Tolerance was significantly better with the BPO/MCZ cream preparation, particularly in female
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