During the statistical analysis of copolymers obtained by the heteropolycondensation method, simulating the difference in the reactivity of the original comonomers by varying the preset reactive conditions, it is shown that the microstructure of the condensation copolymer chains should not depend on the relative reactivity of the comonomers. It is also shown that the microstructure of the chains can be influenced by choosing the copolycondensation conditions in such a way that the process would proceed from a insufficient quantity of the intermonomer in the reactive zone.