AbstractPrevious publication showed that the stereochemistry of lithium aluminum hydride reduction of cyclic ketones can be evaluated by the use of an empirical equation, . This paper reports further test of this relationship in the new system of 2,2‐dimethyl‐4‐t‐butyl‐cyclohexanone.Lithium aluminum hydride reduction of this ketone yields 95.6%trans‐alcohol (lit., 95.9%) corresponding to D̊(D̊G*)Hof 1.67Kcal/mol. With methyllithium, the ketone formed 77.5% oftrans‐alcohol (D̊(D̊G*)D̊fs= 0.67Kcal/mol). These data give a calculatedD̊G* = 0.74Kcal/molwhich agrees well with the literature value of 0.87 or 0.28Kcal/mol.Structural assignments of 2,2‐dimethyl‐4‐t‐butylyclohexanone, 1,2,2‐trimethyl‐cis‐ andtrans‐4‐t‐butylcyclohexanols by