Mutagenic investigation of flavourings: Dimethyl succinate, ethyl pyruvate and aconitic acid are negative in theSalmonella/mammalian‐microsome test
作者:
PiaHaubro Andersen,
NielsJuul Jensen,
期刊:
Food Additives & Contaminants
(Taylor Available online 1984)
卷期:
Volume 1,
issue 3
页码: 283-288
ISSN:0265-203X
年代: 1984
DOI:10.1080/02652038409385855
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Three flavourings: dimethyl succinate, ethyl pyruvate and aconitic acid, commonly used in candy, beverages, and baked goods, were tested in theSalmonella/mammalian‐microsome test. Tester strains were TA 1535, TA 100, TA 1537 and TA 98 and doses were 32, 160, 800, 4000 and 20 000 μg, per plate. All tests were performed with and without the S9 fraction from Aroclor induced rat liver. None of the flavourings showed mutagenic potential. These results support the classification made by the Council of Europe, List I (1981).
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