Reaction of tridentate dithiole ligands (HS–CH2–CH2–X–CH2–CH2–SH. (HSXSH) X = O, S) and monothioles R–SH (butylmercaptane, thiophenoles, and mercaptoacetic acid ethylester) with Tc(V) gluconate yield neutral oxotechnetium (V) complexes TcO(SXS) (SR). Technetium complexes of the individual ligands are found as by products. The reaction was carried out at “carrier-added” level (Tc = 2×10−4mol.l−1) and the reaction products were identified by tlc. The compounds are lipophilic, having octanol/water partition coefficients lg D = 0.78–1.34. Organ distribution studies in rats were estimated.