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The Anti‐Endotoxin Activity of Taurolin in Experimental Animals

 

作者: R. W. PFIRRMANN,   G. B. LESLIE,  

 

期刊: Journal of Applied Bacteriology  （WILEY Available online 1979）
卷期: Volume 46, issue 1  

页码: 97-102

 

ISSN:0021-8847

 

年代: 1979

 

DOI:10.1111/j.1365-2672.1979.tb02586.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

Taurolin, a broad spectrum bactericidal agent, protected experimental animals from the lethal effects ofEscherichia coliandBacteroides fragilisendotoxin. Taurolin also prevented the pyrexic response of rabbits to TAB vaccine. Results suggest that Taurolin exerts its antiendotoxic effect by direct reaction with the endotoxin molecule.

 

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