Current Concepts in Psoriatic Arthritis
作者:
E.M. Veys,
H. Mielants,
期刊:
Dermatology
(Karger Available online 1994)
卷期:
Volume 189,
issue 2
页码: 35-41
ISSN:1018-8665
年代: 1994
DOI:10.1159/000246987
出版商: S. Karger AG
关键词: Psoriasis;Psoriatic arthritis
数据来源: Karger
摘要:
Psoriatic arthritis is an inflammatory arthropathy associated with psoriasis and characterized by absence of rheumatoid factor. Any form of psoriasis can be complicated by joint inflammation. Four groups have been identified: pauciarticular psoriatic arthritis, psoriatic spondylitis, symmetrical polyarticular psoriatic arthritis and arthritis mutilans. The etiology of psoriatic arthritis remains unclear. Genetic, immunologic and environmental factors are thought to be important in the development of the disease. The role of cytokines and adhesion molecules in the mechanism of joint destruction is highlighted, and recent therapeutic strategies are discussed.
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