Ileal adenomas in postcolectomy patients with familial adenomatosis coli/Gardner's syndromeIncidence and endoscopic appearance
作者:
Mitsuo Iida,
Hideaki Itoh,
Toshiyuki Matsui,
Ryuichi Mibu,
Akinori Iwashita,
Masatoshi Fujishima,
期刊:
Diseases of the Colon & Rectum
(OVID Available online 1989)
卷期:
Volume 32,
issue 12
页码: 1034-1038
ISSN:0012-3706
年代: 1989
出版商: OVID
关键词: Polyposis;Ileal adenomas;Familial adenomatosis coli;Gardner's syndrome;Ileoproctostomy
数据来源: OVID
摘要:
&NA;Endoscopy and biopsy of the terminal ileum were performed in 18 patients with familial adenomatosis coli/Gardner's syndrome. All had undergone total colectomy with ileoproctostomy 7 to 249 months (average, 79.7 months) before the study. In all of these patients, endoscopic studies revealed multiple or innumerable small (less than 4 mm in diameter) polypoid lesions, all recognizable, as whitish, sessile elevations. Histologic findings of the biopsy specimens from the polypoid lesions showed tubular adenoma, with or without lymphoid hyperplasia, in nine (50 percent), but only lymphoid hyperplasia in the other nine patients. Colonic metaplasia was present in the adjacent ileal mucosa in 3 patients with ileal adenomas. The incidence (83 percent) of ileal adenomas detected 113 to 249 months after colectomy was higher than that (33 percent) found 7 to 90 months after surgery. In view of these results, endoscopy and biopsy of the terminal ileum, as well as the retained rectum, should be done periodically for postcolectomy patients with this disease
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