Symptomatic, Familial, Perinatal, and Social Correlates of Computerized Axial Tomography (CAT) Changes in Schizophrenics and Bipolars
作者:
GODFREY PEARLSON,
DAVID GARBACZ,
PAUL MOBERG,
HYO AHN,
J. DEPAULO,
期刊:
The Journal of Nervous and Mental Disease
(OVID Available online 1985)
卷期:
Volume 173,
issue 1
页码: 42-50
ISSN:0022-3018
年代: 1985
出版商: OVID
数据来源: OVID
摘要:
Computerized axial tomography (CAT) scans were blindly examined, and lateral ventricular-to-brain ratios calculated in 19 schizophrenic and 27 bipolar patients, and in an equal number of individually matched normal controls. Family history, early development, past psychiatric history, and current functioning and symptomatology were analyzed for all patients. Lateral ventricular enlargement on CAT was found in a significant proportion of both patient groups. Patients with such enlargement tended to have greater numbers of negative symptoms and poorer premorbid adjustment, but did not differ regarding family history of psychiatric illness. A subgroup of schizophrenics with presumed early brain damage was identified. This group had more marked ventricular enlargement, a greater number of negative symptoms, and an earlier onset of illness.
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