Big Endothelin in Spontaneous Intracerebral Hemorrhage
作者:
G.F. Hamann,
E. Isenberg,
M. Strittmatter,
M. Stoll,
T. Keshevar,
R. Moili,
K. Schimrigk,
期刊:
European Neurology
(Karger Available online 1994)
卷期:
Volume 34,
issue 2
页码: 99-102
ISSN:0014-3022
年代: 1994
DOI:10.1159/000117017
出版商: S. Karger AG
关键词: Intracerebral hemorrhage;Big endothelin;Radioimmunoassay
数据来源: Karger
摘要:
Plasma big endothelin (BE) levels were studied in 17 patients during the first 2 weeks following spontaneous intracerebral hemorrhage (ICH). Three patients had experienced an infratentorial hemorrhage of the pons and cerebellum. The group of 14 patients with supratentorial hemorrhage presented with 8 hematomas of the putamen, 4 of the capsula interna and 2 in the thalamus. Significant elevations of BE during the first 2 weeks after the initial ICH, significant differences between the different localisations and between patients with different prognoses were not apparent (mean BE level: 2.95 ± 1.39, control group: 2.68 ± 1.29 fmol/ml). These results support the theory that endothelins do not play a significant pathophysiological role in acute severe IC
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