Coma Blisters in a Case of Fatal Theophylline Intoxication
作者:
Michael Tsokos,
Jan Sperhake,
期刊:
The American Journal of Forensic Medicine and Pathology
(OVID Available online 2002)
卷期:
Volume 23,
issue 3
页码: 292-294
ISSN:0195-7910
年代: 2002
出版商: OVID
关键词: Coma blisters;Theophylline;Intoxication
数据来源: OVID
摘要:
A case of fatal poisoning caused by theophylline toxicity (serum level 127 &mgr;g/ml) is presented. At external examination, skin blisters on regions exposed to pressure were distinctive. Histologic examination demonstrated subepidermal bullae with eosinophilic necrosis of the eccrine sweat gland coil but no epidermal necrosis, vascular changes, or inflammatory infiltrate. To the authors’ knowledge, this is the first description of coma blisters in a case of theophylline intoxication.
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