Similarity of DNA Fingerprints Due to Chance and Relatedness
作者:
C.C. Li,
D.E. Weeks,
A. Chakravarti,
期刊:
Human Heredity
(Karger Available online 1993)
卷期:
Volume 43,
issue 1
页码: 45-52
ISSN:0001-5652
年代: 1993
DOI:10.1159/000154113
出版商: S. Karger AG
关键词: DNA fingerprints;Coefficient of relationship;Relatedness;Population genetics
数据来源: Karger
摘要:
Given the DNA fingerprints of two individuals with some bands being shared by both individuals, we define a new measure of the degree of similarity between the DNA profiles of two individuals. We use this measure to calculate the expected DNA similarity of two unrelated individuals of a randomly mating population; this similarity is due to chance only. Then, the expected similarity between two related individuals is obtained; this similarity is due to chance andrelatedness. From these results, the degree of similarity due to relatedness alone may be calculated.
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