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Similarity of DNA Fingerprints Due to Chance and Relatedness

 

作者: C.C. Li,   D.E. Weeks,   A. Chakravarti,  

 

期刊: Human Heredity  (Karger Available online 1993)
卷期: Volume 43, issue 1  

页码: 45-52

 

ISSN:0001-5652

 

年代: 1993

 

DOI:10.1159/000154113

 

出版商: S. Karger AG

 

关键词: DNA fingerprints;Coefficient of relationship;Relatedness;Population genetics

 

数据来源: Karger

 

摘要:

Given the DNA fingerprints of two individuals with some bands being shared by both individuals, we define a new measure of the degree of similarity between the DNA profiles of two individuals. We use this measure to calculate the expected DNA similarity of two unrelated individuals of a randomly mating population; this similarity is due to chance only. Then, the expected similarity between two related individuals is obtained; this similarity is due to chance andrelatedness. From these results, the degree of similarity due to relatedness alone may be calculated.

 

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