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Epirubicin Treatment of Advanced Breast Carcinoma with the Weekly Low-Dose Regimen

 

作者: G. Beretta,   C. Locatelli,   D. Tabiadon,   R. Labianca,   P. Fraschini,   G. Luporini,  

 

期刊: Oncology  （Karger Available online 1987）
卷期: Volume 44, issue 1  

页码: 6-12

 

ISSN:0030-2414

 

年代: 1987

 

DOI:10.1159/000226434

 

出版商: S. Karger AG

 

关键词: Epirubicin;New anthracyclines;Advanced breast carcinoma;Weekly dose;Second line chemotherapy

 

数据来源: Karger

 

摘要:

Authors describe the results obtained with weekly low-dose (20 or 30 mg/total) of intravenous bolus epirubicin, used as second line chemotherapy, after CMF, in 29 advanced breast carcinoma patients. 29% objective response rate (1 complete + 6 partial responses) has been observed in 24 evaluable patients, with median response duration of 4 months (range 1–7+). The discrete response rate and the minimal incidence of side effects call for further studies and more extensive evaluation of epirubicin given alone or in combination through this new treatment schedul

 

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