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Non-Aqueous Titrimetric Determination of Sulphadimidine Sodium and Sulphadiazine Sodium in Injections

 

作者: SobhiA. Soliman,   Saied Belal,   Mona Bediar,  

 

期刊: Analytical Letters  （Taylor Available online 1985）
卷期: Volume 18, issue 20  

页码: 2497-2505

 

ISSN:0003-2719

 

年代: 1985

 

DOI:10.1080/00032718508064482

 

出版商: Taylor & Francis Group

 

关键词: Potentiometry;Non-aqueous titration;Sulpha drugs analysis;Basicity of sulpha drugs

 

数据来源: Taylor

 

摘要:

The behaviour of sodium salts of two heterocyclic sulphonamide derivatives (Sulphadimidine and sulphadiazine) in non-aqueous titrimetry was studied. Accordingly a simple and accurate procedure for their determination, based on their titration in acetic anhydride-acetic acid solvent system (5:1) with acetous perchloric acid solution is proposed. Results obtained agreed with those of a pharmacopoeial method.

 

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