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Long-term outcomes in small bowel transplantation: Survival, nutrition, growth, and quality of life

 

作者: Simon Horslen,   Debra Sudan,  

 

期刊: Current Opinion in Organ Transplantation  (OVID Available online 2003)
卷期: Volume 8, issue 2  

页码: 202-208

 

ISSN:1087-2418

 

年代: 2003

 

出版商: OVID

 

数据来源: OVID

 

摘要:

Traditional outcomes for transplant recipients include patient and graft survival. Currently, patient survival is between 60 and 75% at 1 year, which is dramatically improved since the introduction of intestinal transplantation just over 1 decade ago. Early graft survival is best for isolated small bowel, but this survival advantage is lost over time. Functional outcomes are also examined in this section. Most patients with intact grafts are able to maintain all of their caloric needs through absorption of nutrients from the intestinal allograft. Growth velocity may improve after intestinal transplantation; however, catch-up growth is uncommon. Quality of life for adult recipients appears to be similar to patients on total parenteral nutrition and for pediatric recipients similar to normal school children. Intestinal transplantation has become a standard therapy for patients with intestinal failure with life-threatening complications of total parenteral nutrition administration.

 

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