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Bioactive Prenylated Hydroquinones from the SpongeSarcotragussp

 

作者: RichardW. Fuller,   MichaelJ. Currens,   JohnH. Cardellina,   MichaelR. Boyd,  

 

期刊: Natural Product Letters  （Taylor Available online 1994）
卷期: Volume 5, issue 3  

页码: 179-181

 

ISSN:1057-5634

 

年代: 1994

 

DOI:10.1080/10575639408044056

 

出版商: Taylor & Francis Group

 

关键词: Sarcotragus;prenylated hydroquinones;cytotoxicity;HIV-1 reverse transcriptase

 

数据来源: Taylor

 

摘要:

Organic extracts of the spongeSarcotragussp. yielded three prenylated hydroquinones, two of which [1,2] were moderately cytotoxic in the NCIin vitroantitumor screen. The third compound [3] was less cytotoxic, but inhibited HIV-1 and HIV-2 reverse transcriptasein vitro.

 

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