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Variation of the Pituitary Response to LH-Releasing Hormone (LH-RH) During a 24-Hour Period in Male, Diestrous Female and Androgenized Female Rats

 

作者: L. Debeljuk,   R. Rozados,   H. Daskal,   C. Villegas Vélez,  

 

期刊: Neuroendocrinology  (Karger Available online 1975)
卷期: Volume 17, issue 1  

页码: 48-53

 

ISSN:0028-3835

 

年代: 1975

 

DOI:10.1159/000122340

 

出版商: S. Karger AG

 

关键词: LH-RH;Pituitary;Gonadotropins;Biological rhythms

 

数据来源: Karger

 

摘要:

The pituitary response to LH-RH was studied at 8 a.m.,4 p.m. and 12 p.m. in normal male rats, female rats on day 1 of diestrus and female rats injected with testosterone propionate on the 2nd day of life. Androgenized rats responded to LH-RH with a greater release of LH than did female diestrous and male rats. In the 3 groups the lowest response to LH-RH was observed at 12 p.m., and the highest at 8 a.m., with the exception of androgenized rats which responded with a similar magnitude of LH release at 8 a.m. and 4 p.m. The release of FSH after the injection of LH-RH was studied only at 4 p.m. and only normal male rats responded with a significant FSH release.

 

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