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Synthesis of epimers of ampicillin

 

作者: G.S.Postnikova,   M.S.Rabinovich,   P.S.Braginskaya,  

 

期刊: Pharmaceutical Chemistry Journal  （Springer Available online 2004）
卷期: Volume 2, issue 1  

页码: 34-38

 

ISSN:0091-150X

 

年代: 2004

 

DOI:10.1007/BF00761099

 

出版商: Springer_US-Boston

 

数据来源: Springer

 

摘要:

1.The potassium salts of N-[1-methyl-2-ethoxycarbonylvinyl]-D(−)-, L(+)-, and DL-α-aminophenylacetic acids were synthesized and their physicochemical properties were studied.2.From the N-substituted D(−)-, L(+)-, and DL-isomers of α-aminophenylacetic acid were synthesized epimers of ampicillin, and their physicochemical and antimicrobic properties were st

 

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