Racial variations in the incidence of congenital malformations
作者:
J. DAVID ERICKSON,
期刊:
Annals of Human Genetics
(WILEY Available online 1976)
卷期:
Volume 39,
issue 3
页码: 315-320
ISSN:0003-4800
年代: 1976
DOI:10.1111/j.1469-1809.1976.tb00135.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SummaryRacial variation in the incidence of several common congenital malformations has been studied in Atlanta, Georgia. The white‐to‐black incidence ratios were substantially different from unity for single defects, while approximate equality of rates was noted for multiple defects. Amongst the specific malformations for which familial data were available, affected first‐ and second‐degree relatives were found only in the families of probands with single defects. It is postulated that these findings may indicate a more prominent function of the environment in the genesis of multiple malformations than is the case for single defects, the occurrence of which may be more strongly affected by non‐sporadic geneti
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