The chemical properties of silica particle surface in relation to silica‐cell interactions
作者:
Xianglin Shi,
N. S. Dalai,
XiangN. Hu,
V. Vallyathan,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1989)
卷期:
Volume 27,
issue 4
页码: 435-454
ISSN:0098-4108
年代: 1989
DOI:10.1080/15287398909531314
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Although silicosis has been studied extensively, the mechanism is still not fully understood. Experiments do provide evidence that the actions of unique properties of silica surface on the cell membrane are the starting point of silicotic processes. This paper summarizes literature on chemical properties of silica surface, and the effect of particle size on silica toxicity. This paper also discusses the ways in which silica dusts are thought to interact with the cell membrane, with emphasis on freshness, hydrogen bonding, and free‐radical interactions.
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