This study addresses the potential impact of natural enemies on the abundance of spider mites,Tetranychusspp., on cotton in the San Joaquin Valley of California. These natural enemies are omnivorous predators, and include the big-eyed bug,Geocoris pallensStål andG. punctipes(Say), the minute pirate bug,Orius tristicolor(White), and the western flower thrips,Frankliniella occidentalis(Pergande). Simple linear regression suggested that omnivorous predators were potentially effective in delaying the buildup of spider mites, with the highestr2(0.65) recorded for adultF. occidentalis.Geocorisshowed the potential to suppress the rate of spider mite population increase (r2= 0.73). All three tested predator species exhibited the capacity to suppress early season spider mite abundance, with the highestr2(0.62) recorded forGeocorisandOrius. Predators were also potentially able to suppress mid- to late-season spider mite populations. Multiple regression analysis indicated a significant negative correlation between mid- to late-season spider mite abundance and early season predators. Results from a second year were less conclusive, suggesting that the reduced range of spider mite abundance limited our ability to discern potentially significant interactions during that year.