Wistar rats retain for months memory of active avoidance learned behaviour
作者:
Giuseppina Mariucci,
Giovanna Bruschelli,
Lorenza Colarieti,
Cristiana Gambelunghe,
MariaVittoria Ambrosini,
期刊:
Italian Journal of Zoology
(Taylor Available online 1998)
卷期:
Volume 65,
issue 3
页码: 311-314
ISSN:1125-0003
年代: 1998
DOI:10.1080/11250008809386764
出版商: Taylor & Francis Group
关键词: Wistar rat;Long‐term memory;Active avoidance;Aging
数据来源: Taylor
摘要:
Male and female Wistar rats, aged 3 months, were massively trained (3.5 h) for a two‐way avoidance task and tested for retention (30 min) the following day. Some of them were subjected to a brief test (30 min) at 5, 10, 15, and 20 months. At 3 months, male rats scored more avoidances and a lower number of escapes, freezings, and intertrial crossings than females; in the test session, both groups improved their performance. Over time, male rats maintained the avoidance score displayed at 3 months. Female rats improved their performance at 5 and 10 months and then, at 20 months, they returned to the level attained at 3 months. These data suggest that active avoidance learning in young animals is fixed as permanent functional changes in the neuronal network of the brain which make aged rats, as well as young adult rats, able to master the task.
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