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Wistar rats retain for months memory of active avoidance learned behaviour

 

作者: Giuseppina Mariucci,   Giovanna Bruschelli,   Lorenza Colarieti,   Cristiana Gambelunghe,   MariaVittoria Ambrosini,  

 

期刊: Italian Journal of Zoology  (Taylor Available online 1998)
卷期: Volume 65, issue 3  

页码: 311-314

 

ISSN:1125-0003

 

年代: 1998

 

DOI:10.1080/11250008809386764

 

出版商: Taylor & Francis Group

 

关键词: Wistar rat;Long‐term memory;Active avoidance;Aging

 

数据来源: Taylor

 

摘要:

Male and female Wistar rats, aged 3 months, were massively trained (3.5 h) for a two‐way avoidance task and tested for retention (30 min) the following day. Some of them were subjected to a brief test (30 min) at 5, 10, 15, and 20 months. At 3 months, male rats scored more avoidances and a lower number of escapes, freezings, and intertrial crossings than females; in the test session, both groups improved their performance. Over time, male rats maintained the avoidance score displayed at 3 months. Female rats improved their performance at 5 and 10 months and then, at 20 months, they returned to the level attained at 3 months. These data suggest that active avoidance learning in young animals is fixed as permanent functional changes in the neuronal network of the brain which make aged rats, as well as young adult rats, able to master the task.

 

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