Can Collagen Metabolism Be ControlledTheoretical Considerations
作者:
I. COHEN,
期刊:
The Journal of Trauma: Injury, Infection, and Critical Care
(OVID Available online 1985)
卷期:
Volume 25,
issue 5
页码: 410-412
ISSN:0022-5282
年代: 1985
出版商: OVID
数据来源: OVID
摘要:
SUMMARYPharmacologic alterations of the inflammatory response and collagen metabolism will lead to control of the many disease states of fibrosis. Many of these diseases kill and cripple far more than hypertrophic scar. Far too little research is being directed in this area. The objectives of controlling fibrosis by interfering with collagen crosslinking were defined clearly by Peacock. Perhaps topical BAPN will be the first agent to bring a practical clinical reality to his predictions made over 20 years ago.
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