A study of ethers for the selection of candidates for carcinogen bioassay*
作者:
C. T. Helmes,
C. C. Sigman,
D. L. Atkinson,
P. A. Papa,
K. L. Thompson,
M. A. Valentini,
K. E. McCaleb,
E. S. Bulian,
P. A. Rich,
期刊:
Journal of Environmental Science and Health . Part A: Environmental Science and Engineering
(Taylor Available online 1983)
卷期:
Volume 18,
issue 6
页码: 797-839
ISSN:0360-1226
年代: 1983
DOI:10.1080/10934528309375143
出版商: Taylor & Francis Group
关键词: Ethers;Carclnogenicity;Bioassay;Review
数据来源: Taylor
摘要:
The class of ether compounds was studied in order to nominate chemicals to the National Cancer Institute as candidates for carcinogen bioassay. After application of several qualifying criteria relating to previous, current, or planned carcinogenlcity tests and to commercial significance, the preliminary candidate list of 323 chemicals was reduced to a list of 176 chemicals. Based upon consideration of both the suspicion of possible carcinogenic activity and evidence indicating potential exposure, the following eight chemicals were nominated: methyleugenol, isoeugenol, 2‐isopropoxyphenyl N‐methylcarbamate, estragole, 2‐hydroxy‐4‐methoxybenzophenone, tetrahydrofuran, methyl vinyl ether, and diphenyl ether.
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