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A study of ethers for the selection of candidates for carcinogen bioassay*

 

作者: C. T. Helmes,   C. C. Sigman,   D. L. Atkinson,   P. A. Papa,   K. L. Thompson,   M. A. Valentini,   K. E. McCaleb,   E. S. Bulian,   P. A. Rich,  

 

期刊: Journal of Environmental Science and Health . Part A: Environmental Science and Engineering  (Taylor Available online 1983)
卷期: Volume 18, issue 6  

页码: 797-839

 

ISSN:0360-1226

 

年代: 1983

 

DOI:10.1080/10934528309375143

 

出版商: Taylor & Francis Group

 

关键词: Ethers;Carclnogenicity;Bioassay;Review

 

数据来源: Taylor

 

摘要:

The class of ether compounds was studied in order to nominate chemicals to the National Cancer Institute as candidates for carcinogen bioassay. After application of several qualifying criteria relating to previous, current, or planned carcinogenlcity tests and to commercial significance, the preliminary candidate list of 323 chemicals was reduced to a list of 176 chemicals. Based upon consideration of both the suspicion of possible carcinogenic activity and evidence indicating potential exposure, the following eight chemicals were nominated: methyleugenol, isoeugenol, 2‐isopropoxyphenyl N‐methylcarbamate, estragole, 2‐hydroxy‐4‐methoxybenzophenone, tetrahydrofuran, methyl vinyl ether, and diphenyl ether.

 

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