Circadian rhythm of neuropeptide Y-like immunoreactivity in the iris-ciliary body of the rat
作者:
OtoriYasumasa,
CagampangFelino Ramon A.,
YamazakiShin,
Ichi T.Shin,
ManoTomiya,
TanoYasuo,
期刊:
Current Eye Research
(Taylor Available online 1993)
卷期:
Volume 12,
issue 9
页码: 803-807
ISSN:0271-3683
年代: 1993
DOI:10.3109/02713689309020385
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Neuropeptide Y (NPY)-like immunoreactivity (LI) in the irisciliary body of rats kept under constant darkness (DD) and in 12 h light-12 h dark cycle (LD) was determined by enzyme immunoassay. NPY-LI contents in the iris-ciliary body were found to oscillate in circadian fashion under DD and LD conditions, with a peak at about circadian time 12 (CT 12) and a trough at around CT 0. Unilateral superior cervical ganglionectomy caused a significant decrease in NPY-LI levels in the sympathectomized eye compare to the contralateral intact eye, independent of lighting phase. These results suggest the presence of an endogenous circadian rhythm in NPY-LI content in the rat iris-ciliary body, and the possible involvement of a sympathetic input from the superior cervical ganglion.
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