Local recurrence following ‘curative’ surgery for large bowel cancer: I. The overall picture
作者:
R. K. S. Phillips,
Rosemary Hittinger,
Lynda Blesovsky,
J. S. Fry,
L. P. Fielding,
期刊:
British Journal of Surgery
(WILEY Available online 1984)
卷期:
Volume 71,
issue 1
页码: 12-16
ISSN:0007-1323
年代: 1984
DOI:10.1002/bjs.1800710104
出版商: John Wiley&Sons, Ltd.
关键词: Colonic neoplasms;rectal neoplasms;neoplasm recurrence;local
数据来源: WILEY
摘要:
AbstractThe Large Bowel Cancer Project is a collaborative prospective study of 4228 patients with a histologically proven adenocarcinoma, of whom 2336 (55 per cent) survived a ‘curative’ resection. Follow‐up information is available on 2220 patients (95 per cent). Subsequently, 309 (14 per cent) have developed a local recurrence confirmed by: biopsy (127; 41 per cent), clinical examination (77; 25 per cent), X‐ray (15; 5 per cent), a raised CEA (2; 1 per cent), or some other method — e.g. CT scan or a confident unbiopsied laparotomy finding (88; 29 per cent).Statistically significant factors (χ2test, P<0.05) associated with local recurrence are: Dukes' classification: A 4 per cent; B 13 per cent; C 18 per cent Tumour differentiation: Well 11 per cent; Moderate 14 per cent; Poor 21 per cent Obstruction: Absent 13 per cent; Present 21 per cent Perforation: Absent 13 per cent; Present 28 per cent Tumour mobility: Freely mobile 11 per cent; Others 21 per cent Operation performed (rectal and rectosigmoid tumours): Abdomino‐perineal 12 per cent; Anterior resection 18 per cent; Surgeon (Consultant only): Range20 per cent. Stratification of the above variables altered only the statistical significance pertaining to tumour differentiation (P<0.1, d.f. = 2). In particular, the differences between Consultant surge
点击下载:
PDF
(570KB)
返 回