A Large Primary Malignant Melanoma of the Female Urethra Presenting as Postmenopausal Vaginal Bleeding
作者:
Frank Van der Aa,
Steven Joniau,
Hendrik Van Poppel,
Ignace Vergote,
Raymond Oyen,
Kristof Cokelaere,
Luc Baert,
期刊:
Journal of Pelvic Surgery
(OVID Available online 2002)
卷期:
Volume 8,
issue 1
页码: 47-49
ISSN:1077-2847
年代: 2002
出版商: OVID
数据来源: OVID
摘要:
BackgroundPrimary malignant melanoma of the female urethra is a rare pathology. Treatment options are still debated.CaseThe authors describe a patient with a primary malignant melanoma of the urethra 5.4 cm in diameter presenting as postmenopausal vaginal bleeding and treated with anterior pelvic exenteration. No adjuvant therapy was administered. The patient died of pneumonia shortly after discharge.DiscussionHistogenesis, diagnosis, therapy, and prognosis of malignant melanoma are discussed briefly.ConclusionSuccessful treatment of malignant melanomas of the urethra has been reported. These tumors should be treated aggressively. The role of adjuvant &agr;-interferon and chemotherapy is currently under investigation. Involvement of lymph nodes and depth of invasion are important prognostic factors.
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